Sr. Research Associate - Gene Therapy

Back to jobs New Sr. Research Associate - Gene Therapy Watertown, Massachusetts, United States Apply Now The Role Senior Research Associate As a hands-on molecular biology expert, you will play a key role in advancing Dyno’s animal studies to identify and develop cutting-edge muscle AAV-based capsids. You will process and analyze tissues from in vivo studies, support histology workflows, and conduct in vitro experiments to characterize leading capsids and capsid libraries. Working closely with Research Associates, Scientists, and Computational Biologists, you will help the Muscle team generate high-quality data that shapes the future of gene therapy. Job Type: Full Time Location: Watertown How You Will Contribute As a Senior Research Associate, you will provide hands-on experimental support across tissue processing, molecular measurements, histology, and in vitro characterization. You will work alongside a team of talented scientists and contribute to a diverse range of projects. Your role will require you to optimize workflows, troubleshoot problems, and ensure successful project outcomes by aligning with team goals. At Dyno, every role is mission-driven. Whether in science, engineering, operations, or business, each AAViator contributes to solving some of the most complex challenges in genetic medicine. Responsibilities:  Sample inventory and dissection of tissues (mammalian cells, non-human primate and mouse tissues). Extract, purify, and enrich nucleic acids from mammalian cells and tissues.  Run quantification assays on purified nucleic acids (e.g., qPCR, RT-qPCR). Prepare next-generation sequencing libraries (amplicon sequencing) and perform associated QC steps. Support histology workflows, including tissue preparation, sectioning, staining, imaging, and analysis. Maintain mammalian cell cultures and execute cell-based experiments to characterize leading muscle capsids and capsid libraries. Analyze experimental data, identify technical issues, and re